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glutathione formaldehyde dehydrogenase - an overview The requirement for the glutathione-dependent
Description
2005 Mar;62(6):708-16
Hemoglobin is discussed in Chapter 5
GSH reacts with ROS species and gets transformed to GSSG causing a decline in GSH/GSSG ratio that results in oxidative stress 10,11
Together, these reports indicating that cells resistant to antimony-(III) are not resistant to stibogluconate [antimony-(V)] lead us to the hypothesis that gluconate could be an, if not the, active anti-cancer substance in this scenario
