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and Kojima, I
Impact of PM on the Cardiovascular System PM can penetrate deep into the lungs and enter the bloodstream, triggering systemic inflammation, oxidative stress, as well as endothelial dysfunction, and thereby poses significant dangers also to the cells and tissues of the cardiovascular system
This activation inhibits the nuclear factor-kappa B (NF-B) and p38 mitogen-activated protein kinase (p38MAPK) signaling pathways [72], reducing IL-1production in astrocytes and attenuating neuroinflammation [73]
The glycocalyx: a key target for treatment of severe acute pancreatitis-associated multiple organ dysfunction syndrome
