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FOXO4-DRI effectively improves vascular function in prematurely aging mice To further explore the role of FOXO4-DRI in aged mice, we constructed prematurely aging mouse model by administering D-galactose (200 mg/kg) intraperitoneally for 8 weeks

The overexpression of mitochondrial ferritin has been shown to inhibit oxidative stress, which in turn mitigates ferroptosis (138)
