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Vitamin B12 absorption from food requires several steps: intrinsic factor secretion from gastric parietal cells, acid-dependent release of B12 from food proteins, and physical contact time in the ileum where transcobalamin receptors capture the B12-intrinsic factor complex
Mol Neurobiol 53:41974200
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However, the best results typically develop over the course of 3 to 6 months
