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Galera will need to provide results from an additional clinical trial in order to resubmit the application, the Malvern, Pennbased company said in a press release
ROS derived from the Nox subtypes Nox1, Nox2, and Nox4 lead to vascular dysfunction in diabetic retinopathy, and Nox5-derived ROS increase the incidence of abdominal aortic aneurysms in diabetic patients [16, 17]
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