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When NAD levels decline, mitochondrial activity in neural tissue can become less efficient

doi: 10.1073/pnas.1117773108 101 MullenARWheatonWWJinESChenPHSullivanLBChengTet al
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Therapeutic strategies developed and tested in the past Significant progress has been made by the neurofibromatosis research community, including the genetic cause of NF1, the cellular function of the neurofibromin protein, and the identification of cellular components that contribute to the tumours developed in NF1
