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Pre-symptomatic neurodevelopmental issues and early Nrf2 deficits are now well documented
Head-to-head trials show Mounjaro produces greater weight loss (1522% vs 1215%) and greater HbA1c reduction for diabetes
This is significant because during aerobic contractile activity, skeletal muscle mitochondria are predominantly in state 3 and this limits their generation of ROS during contractions (104, 160, 225)
Release 317 , 273281 (2020)
