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Among the classical inflammasome pathway, Nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome-mediated pyroptosis is the most extensively studied phenomenon and can be activated by different stimuli, first of all, ROS
CR prevents aging and aging-related diseases, in part through autophagy and reversing abnormal aging-related epigenetic alterations
10.1210/en.2014-1690 96 DonatoA
