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These effects were achieved through direct inhibitory actions on prostatic GH-RH receptors, as evidenced by significant tissue-specific reductions in levels of NF-B/p50, cyclooxygenase-2, and androgen receptors, and changes in the expression of over 90 genes related to growth, inflammation, and signal transduction
L.ZhangY.LiX.FuQ
Napolitano S, Woods M, Lee HM, De Falco V, Martini G, Della Corte CM, Martinelli E, Famiglietti V, Ciardiello D, Anderson A, Fowlkes NW, Villareal OE, Sorokin A, Kanikarla P, Coker O, Morris V, Altucci L, Tabernero J, Troiani T, Ciardiello F, Kopetz S
