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After complete mechanical tissue disruption, about 12 mol aliphatic and 3 mol indolic glucosinolates per gram fresh weight ( in vivo , it remains to be clarified how deep endogenously produced ITCs can penetrate into intact tissues
It encourages the differentiation of macrophages into pro-fibrotic M2 phenotypes and an increase in extracellular matrix synthesis, which exacerbates renal fibrosis
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Montgomery M, Srinivasan A
