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Heightened inflammation: Dysregulated NF-kB pathways promote pro-inflammatory cytokines

[28] found that NNMT knockdown significantly reduced the body weight, fat mass, and insulin level of female mice fed a Western diet (fat 47% kcal, carbohydrate 34% kcal), as did NNMT knockout

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Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work