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CRBN-DDB1 Protein, Human (Biotinylated, sf9, Avi) forms a CRBN:MGD:CRBN ternary complex with MRT-31619 (HY-180538) [2]

Furthermore, correlation analysis between molecular biomarkers on both measured gene and protein levels against clinical outcomes, specifically intraocular pressure (IOP) reduction across different animals within the same treatment group was done to examine how the molecular expression patterns align with physiological responses

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Due to the lack of efficacy of the above-mentioned management strategies for CIPN, in recent years the focus has shifted to delineating the molecular mechanisms underlying CIPN, with the view to identify mechanism-specific treatment targets