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Since vitamin B 12 is a determinant of homocysteine metabolism, it was suggested that the risk of osteoporotic fractures in older subjects might be enhanced by vitamin B 12 deficiency

Fenton reaction refers to a set of chemical reactions involving H 2 O 2 and transition metal ions, typically Fe 2+ , which generates OH, one of the most reactive ROS

While it is clear that organ transplant recipients should not actively raise their glutathione levels, those who are on immuno-suppressive therapies might actually benefit from glutathione supplementation to normalize the immune system instead of depressing it, but this approach must be taken very carefully
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