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Proc Natl Acad Sci 106(6):20472052 Carroll MR, Rodd ZA, Murphy JM, Simon JR (2006) Chronic ethanol consumption increases dopamine uptake in the nucleus accumbens of high alcohol drinking rats

Nat Genet 40: 249254 [DOI] [PubMed] [Google Scholar] Dean NL, Battersby BJ, Ao A, Gosden RG, Tan SL, Shoubridge EA, Molnar MJ 2003

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This helps explain why patients with extensive surgical trauma or prolonged ischemia often develop a systemic inflammatory response that parallels septic shock, even in the absence of infection ( Importantly, these pathways offer targets for intervention: blocking upstream mtDAMPs release or downstream receptors could blunt the harmful inflammation