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Vials come in different strengths (such as 5 mg or 10 mg), and mixing the wrong amount of water changes your entire dosing schedule

caution in those at risk of diabetes

Standard maintenance: - Type I-II: 0.5 mg twice per week - Type III-IV: 0.5 mg once per week - Type V-VI: 0.5 mg every 2-3 weeks Alternative approach: Some users prefer a single larger weekly dose (1.0 mg once per week instead of 0.5 mg twice per week)

1 Hydroxocobalamin can also act as a scavenger of peroxynitrites that may build up in the body (particularly for those who may have COMT & other such mutations), converting the reactive oxidant back into methionine