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To avoid the unspecific cleavage of APC-specific substrate by thrombin, residual activity of thrombin was inhibited by addition of recombinant hirudin (Refludan, Bayer Health Care)

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However, very limited information is available about the exact metabolic functions of disease-induced GST isoenzymes and about their endogenous substrates

JenthoENovakovicBRuiz-MorenoCKourtzelisIMartinsRChavakisTet al
