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Description
Chosen solvent (BAC, saline, etc) sterile filtered
Metformin exerts its antitumor effects mainly through the AMPK/LKB1/mammalian target of rapamycin (mTOR) complex 1 (mTORC1) signaling pathway, causing apoptosis of cancer cells (4548)
Ease of use and dosage forms Both methods come in formats that work for different people
Briefly, either the liver portion or the kidney tissue specimens were combined with PBS (pH 7.4) and centrifuged for 20 min at 1,200 g at 4C to obtain the supernatant fluid (42)
