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Description
Unlike other drugs such as Mounjaro and Zepbound, which activate both GLP-1 and GIP receptors, MariTide works as a GLP-1 receptor agonist and a GIP receptor antagonist

Even more telling, gastrointestinal side effects causing treatment discontinuation were lower with tirzepatide (2.7%) than semaglutide (5.6%)

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The peptide's 2030 hour half-life means peak plasma concentration occurs 46 hours post-injection
