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Metabolic flux analysis further reveals that this lactate shuttle relies on AMP-activated protein kinase (AMPK)-mediated glycolytic activation in astrocytes and dynamic regulation of mitochondrial pyruvate carriers in neurons, providing both energy and signaling support for synaptic structural remodeling essential for memory formation (Yellen, 2018)

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This study showed that perindopril preserved the goblet cells in the villi/crypts and reduced the histological abnormalities, indicating that the intestinal injury had been attenuated
Masoodi M, et al
