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The ubiquitous activation of HIF-1 is thus consistent with the significant role that this factor plays in coordinating adaptive responses to hypoxia [52, 53]

10.1002/ptr.3446 112 ZhangQ.FengZ.LuJ.LuJ.GuanS.ChenY

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The tissue was homogenized in Assay buffer and the concentration of all samples was adjusted to 3.9 mg/ml
