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Moreover, as the negative effects of DMSO on the cell membrane are well known [1,2,3,15], in parallel to studies involving the direct addition of DMSO to the culture medium, a second method of administration was usedthe partial insertion of DMSO into polymerosomes (poly(ethylene glycol) and poly(lactide-co-glycolide) methyl ether block, PEG-PLGA) aimed at eliminating these potentially destructive effects

In addition, other cell types, such as fibroblasts, play important roles in promoting tumor growth and metastasis, providing growth factors and contributing to extracellular matrix remodeling with matrix metalloproteinases [148, 149]

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Rv0884c inhibits IFN- production in CD8 + T cells To show that d-serine produced by Mtb via Rv0884c during infection could have the same effect as exogenously applied d-serine, we performed experiments with Rv0884c-knockdown or complemented strains as above