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doi: 10.3389/fphar.2021.699245 Received 23 April 2021 Accepted 09 June 2021 Published 14 July 2021 Volume 12 - 2021 Edited by Hua Jin, Guangdong Medical University, China Reviewed by Juanzhu Yan, University of North Carolina at Chapel Hill, United States Antoine Dufour, University of Calgary, Canada Updates Copyright 2021 Li, Su, Cai and Liu