bpc-157 full name body protection compound-157 Peptide BPC-157 – Mark Hyman, MD

At the molecular level, 5-amino-1MQ functions as a competitive inhibitor of NNMT, demonstrating remarkable potency with an IC of 1.2 0.1 M under standard assay conditions (50 M SAM, 100 M nicotinic acid). This represents a dramatic 10-fold improvement over the parent compound 1-methylquinolinium, achieved through strategic amino group substitution that enhances binding affinity to the NNMT active site. The compound's mechanism centers on preventing the methylation of nicotinamide to 1-methylnicotinamide (1-MNA), thereby preserving nicotinamide for recycling back to NAD+ through the salvage pathway. This intervention effectively blocks what researchers have termed the "NNMT metabolic drain" a process that simultaneously depletes NAD+ precursors and consumes cellular methylation capacity

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Ganjam G.K., Bolte K., Matschke L.A., Neitemeier S., Dolga A.M., Hllerhage M., Hglinger G.U., Adamczyk A., Decher N., Oertel W.H., et al

A Safety Data Sheet and a brief handling reference are included alongside the COA in the package

Individuals with Digestive Issues: Conditions like Crohns disease, celiac disease, and gastric surgeries can hinder B12 absorption