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The protein expression of the IL-36 agonist was verified by immunohistochemical labeling and increased mRNA expression of IL-36 cytokines, particularly IL-36Ra, in psoriatic skin lesions in various cells such as keratinocytes, endothelial cells, dermal fibroblasts, dendritic cells, and CD68 + macrophages

C., Lopes, J

Analysis of the percentages of circulating Th1 (CD4 + IFN + ), Th2 (CD4 + IL4 + ) and the CD4 + CD25 + CD127 low regulatory T cells as well as the Th17 (CD4 + IL17A + ) cells revealed intriguing data suggesting the suitability of the HFD-dNONcNZO mice for studying obesity-induced immunological alterations and dysfunctional ovarian responses during early gestation in individuals with features of PCOS

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