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doi: 10.1210/en.2017-00348 165 ZhengFZhangSLuWWuFYinXYuDet al

Abemaciclib is effective against pancreatic cancer cells and synergizes with HuR and YAP1 inhibition

Its headline job is to ferry long-chain fatty acids into mitochondria so they can be oxidized for energy

The entire distal CTD is stabilized primarily through coiled-coil interactions, which may have relatively low stringency for amino acid side chains, and thus could account for the low sequence conservation (Singer et al., 2002
