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Using these genome-wide linkage methods the first major susceptibility locus for type 2 diabetes was located on chromosome 2 in 1996

doi: 10.1016/j.clindermatol.2010.03.002

Indications for surgery Transsphenoidal surgery (TSS) performed by an experienced neurosurgeon can achieve initial normoprolactinaemia in up to 93% of individuals with microprolactinomas and 75% of those with selected macroprolactinomas 6,9
