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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

Following AAV-shRNA delivery, mice were fed a MASH-inducing diet rich in fat, cholesterol and fructose, which better recapitulates human liver inflammatory pathology 34 (Fig
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Retatrutide produces higher rates of nausea (43% vs 20-47%), diarrhea (33% vs lower), and vomiting (21% vs lower) at their respective maintenance doses