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Irisin, cleaved from FNDC5, crosses the bloodbrain barrier (BBB) and upregulates BDNF in the hippocampus, promoting synaptic plasticity and neurogenesis

[DOI] [PMC free article] [PubMed] [Google Scholar] Moriggi M., Cassano P., Vasso M., Capitanio D., Fania C., Musicco C., Pesce V., Gadaleta M.N., Gelfi C

By analyzing the KO content, organisms and samples can be clustered, revealing distinct groups with unique characteristics

Current research explores various formulations to improve therapeutic utility
