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B sung c lng Glutathion cn thit m li rt d ung, sng khoi, th thi

2 Structure and mechanism of action of ADCs 2.1 Key components of ADC The concept of ADCs was first presented by Paul Ehrlich almost 100 years before

The major pathways that regulate ferroptosis include glutathione peroxidase 4 (GPX4)-glutathione (GSH), ferroptosis-suppressor-protein 1 (FSP1)-CoQ 10 , FSP1-vitamin K (VK), dihydroorotate dehydrogenase (DHODH)-CoQ, and GTP cyclohydrolase 1 (GCH1)-tetrahydrobiopterin (BH 4 )

Wang, Liang-Jen, et al