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Several studies are still ongoing, including those involving other vitamin E isoforms (86)

discovered that downregulation of mTOR in LN patients leads to a reduction in STAT3 and Th17 cells within effector T cells, while inhibiting the AKT signaling pathway hinders the migration of Th17 cells towards inflammatory sites, effectively mitigating the chronic inflammatory process in LN (38, 156)

10.2217/epi-2016-0002 [DOI] [PMC free article] [PubMed] [Google Scholar] Lean J

Some animal studies have reported re-pigmentation in gray hair follicles following exposure to this compound, mediated through effects on melanocyte activity in the follicle