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Description
Several of these kinases are constitutively active in certain cancers, and this promotes uncontrolled cell growth

IRF3, a downstream target of STING, is also involved in lipid peroxidation and ferroptosis

Cancer Cell 19 , 498511 (2011)

MLL-AF9 expression in hematopoietic stem cells drives a highly invasive AML expressing EMT-related genes linked to poor outcome
