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The modulation of c-MET pathway activity by TGF- allows to speculate that subsets of patients with glioblastoma would have responded to TGF- inhibitors such as galunisertib (LY2157299 monohydrate) with an increase of c-MET activity and potentially MET-mediated migration and invasion

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In this study, CiteSpace presented the co-citation relationships of references and clusters in a timeline with parameters set to time slice (20122022), year per slice (1), node type (cited references), selection criteria (top N = 50) and pruning (Pathfinder)