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Activation of MC4R increases libido and may contribute to improved sexual function, which has been confirmed in animal studies and in some clinical trials

Vincent Canby reviewed the film negatively, and was critical of De Niro's casting: "De Niro, who was very fine as the street-wise priest in True Confessions , is all right here until he opens his mouth." [77] However, the film won an Academy Award for Best Cinematography, three BAFTAs, including Best Editing, and two Golden Globes for Best Screenplay and Best Original Score
