most glutathione peroxides are selenium dependent containing selenium as and Selenoproteins: Mechanisms, Health Functions, and Emerging Applications Effects of selenium and glutathione
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& Ranieri, G
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Sodium and potassium are also involved in neuronal transmission with the ionotropic glutamate receptors (NMDA, AMPA)
This explicit requirement for lipid peroxidation is a core feature of ferroptosis that distinguishes it from other forms of cell death: ferroptosis inhibitors cannot prevent other forms of cell death (Yang et al., 2014), and conversely classic inhibitors of necrosis, apoptosis, and autophagy do not modulate ferroptosis ( Figure 1 )
