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Furthermore, Bui et al (71) demonstrated that treatment of intestinal epithelial cells or hepatocytes with SCFAs, particularly butyrate, notably upregulated the expression and activity of 17-hydroxysteroid dehydrogenase and 3-hydroxysteroid dehydrogenase

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Caused a slight, non-significant decrease in acetyl CoA levels in rats fed a 30% fat plus 20% 1,3-butanediol diet

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Class 1 UM has low or medium metastatic potential, while the Class 2 UM present high metastatic potential with the deletion of chromosome 3

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10.1016/j.jpain.2013.08.002 23 Di Cesare MannelliL.PaciniA.MateraC.ZanardelliM.MelloT.De AmiciM.et al (2014)

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