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This step is particularly important as Glu and Cys are linked by a stable -peptide bond instead of the typical -peptide linkage, thus providing a stronger resistance to the action of most intracellular enzymes [18]

The thermodynamic equilibrium constant (6 10 15 M) favors the reductive amination of glutamate (Engel & Dalziel 1967)
PMID: 42143359 J Nanobiotechnology2023 Aug 25;21(1):294
The triple power of D: Protein intrinsic disorder in degenerative diseases
