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The purity of these M pro s was greater than 95% by LDS-gel electrophoresis, RP-HPLC chromatography (205 nm), and MALDI-TOF analysis (see Figure S1B-S1E in supplemental material), with an average experimental mass of 33796 amu +/ 1 amu (expected average mass of 33796.48 amu) (see Figure S1E and S1I (insets) in supplemental material)
