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Description
This change frees Nrf2 from its binding with Keap1, allowing it to translocate to the nucleus

For dose-response cytotoxicity experiments, use at least 810 compound concentrations spanning 34 logs to accurately determine IC50 values

10.1086/377267 254 SouyrisF.PellequerC.PayrotC.ServeraC

Oral, topical, and mechanical therapies generally have little evidence supporting their efficacy
