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** The NRV percentage for adults has not been determined
Those who are concerned or particularly sensitive can request additional pre-injection numbing injections with lidocaine or can use ice prior to injection to numb the treatment area (avoiding the initial pin-prick of Vollure)

Consistently, human studies demonstrated that l-ARG improved arterial hypertension after both acute intravenous infusion [53] and oral supplementation of l-ARG for 3 months in addition to antihypertensive drugs [54]

doi: 10.1038/bjc.2012.306
