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In breast cancer tissue, miR-873 was downregulated compared to normal mammary tissue, resulting in increased PD-L1, a target of miR-873 [90]

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Mitophagy is the selective autophagic removal of damaged mitochondria, crucial for mitochondrial quality control

These changes increase the peptides resistance to enzymatic degradation , allowing it to remain active in the bloodstream longer and prolonging its half-life
