glutathione-synthesizing enzymes Glutathione Metabolism - an overview Frontiers | Redox regulation of
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Indeed, PPAR overexpression and CPT1 inhibition demonstrated that oxalate impairs mitochondrial respiration mainly through the suppression of FAO
In fact, some trials observed slight improvements in metabolic markers, likely secondary to fat loss rather than direct peptide effects
Therefore, inhibiting SLC7A11 can interfere with the synthesis of glutathione in tumor cells and disrupt the oxidative-reductive homeostasis of cancer cells (Zhang et al., 2018)
