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This targeting strategy makes SS-31 particularly effective in protecting high-energy-demand tissues such as heart, skeletal muscle, kidney, and brain from mitochondrial dysfunction associated with ischemia, aging, metabolic diseases, and neurodegenerative conditions

[DOI] [PubMed] [Google Scholar] Cobb MH, Heagy W, Danner J, Lenhoff HM, Marshall GR

It was interesting to note that, at the higher concentrations of 0.5ug/ml and 1 g/ml, we observed lower rate of telomere extension for BT474 when compared to the maximum length obtained at 0.2ug/ml