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Based on the data available in 2015, EFSA did not identify any known health risks associated with the use of dietary supplements, so no maximum dose or maximum daily intake, also known as a tolerable upper intake, was set (EFSA, 2015)

Life Sci 234:116776 Yaribeygi H, Katsiki N, Butler AE, Sahebkar A (2019b) Effects of antidiabetic drugs on NLRP3 inflammasome activity, with a focus on diabetic kidneys

Photoageing Models: UV Biology UVB irradiation (311 nm narrowband or 295315 nm broadband at 50200 mJ/cm doses) in HDFs produces: CPD (cyclobutane pyrimidine dimer) formation (anti-CPD immunoassay, comet assay tail moment)

Part of the reason could be that arbutin does not form hydrogen bonds with the residues in the C1 region (Table 2).The RMSF values of the residues surrounding Arbutin_c and Arbutin_d were generally low