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For instance, NR supplementation in preclinical studies has been shown to reduce chemotherapy-induced peripheral neuropathy, inhibit cancer metastasis, and, in some cases, enhance tumor-suppressive effects. A brief summary of these findings can be found below in the Appendix in Table 1, illustrating that NAD+ metabolism is complex and may be protective under certain conditions

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The Phase II data showed statistically significant weight loss versus placebo at several dose levels but the magnitude was modest (roughly 1.5-2.5kg over 12 weeks at optimal doses)

Traditional hormone therapies often use synthetic or animal-derived hormones that are similar, but not identical, to those found in the human body