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Redox Biol 2: 786794, 2014 [DOI] [PMC free article] [PubMed] [Google Scholar] 25.Jain SK, Kahlon G, Bass P, Levine SN, and Warden C

Thus, according to the cytokine hypothesis, it is reasonable to believe that these pro-inflammatory cytokines can then increase the risk of depression through ways such as inhibiting the negative feedback of the HPA axis, increasing the permeability of the BBB, and so on

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This applies to both the initial reconstitution and every subsequent dose draw
