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For negative controls, ubiquitin buffer was added instead of the E1 and E2

Macrophage reprogramming within the tumour microenvironment is determined by intricate phenotypic and functional shifts shaped by M1 or M2 polarisation, metabolic and epigenetic changes, and multiple signalling pathways

Our typical clinic protocol for ketosis treatment is 3-5 days of glycol along with Vitamin B12

MTHFR activity is greatly diminished in heterozygous 677C/T (-30%) and homozygous 677T/T (-65%) individuals compared to those with the 677C/C genotype (23)
