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In summary, from these experimental results, the effects of TMAO on NO bioavailability are inconsistent, and it appears that only pharmacological concentrations of TMAO could have a negative effect in normal metabolic conditions

Although various attempts have been made to discover metabolite biomarkers for the diagnosis and treatment response of MDD, problems with sample size and consistency of results have limited clinical application

Mild gastrointestinal symptoms (transient nausea, vomiting, abdominal cramps and diarrhea) have been reported

Cysteine is found in high-protein foods, especially: Poultry (chicken, turkey) Eggs Beef and pork Dairy products (milk, yogurt, cheese) Legumes (lentils, chickpeas, soy) Nuts and seeds Whole grains (oats, wheat germ) Cruciferous vegetables like broccoli and Brussels sprouts also support cysteine production through their sulfur content