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Cell-based phospho-Met ELISA EHMES-1 cells (2 10 4 cells per well) were seeded in a 96-well black Clear-plate (Greiner Bio-One)

Several factors contribute to the increased risk of colon cancer in individuals with obesity, including alterations in systemic growth factors, visceral adipose tissue, the microbiome, bile acids, inflammation, and a diet rich in fat, sugar, high fructose corn syrup, or low vitamin D

It can impair the activity of the lysosomal calcium channel MCOLN1/TRPML1, leading to the formation of enlarged, dysfunctional lysosomes and autophagosomes (Raju and Jones, 2010)

Overcoming platinum and parp-inhibitor resistance in ovarian cancer