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PMID: 29581842

The authors concluded that, as opposed to a spontaneous regression period of 1-5 years, intravaginal topical application of BC significantly shortens the regression time of low-grade cervical intraepithelial lesions to half a year (Stefani et al., 2014)

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36 Besides, platinum-based drugs such as cisplatin, carboplatin, and oxaliplatin have been widely used in clinical practice, but adverse effects and resistance increased due to lack of specificity, while platinum nanoparticles can be used to overcome these limitations of free drugs, such as targeting defects and uncontrolled drug release
