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doi: 10.1007/s11060-019-03103-4 259 RosenthalMAKavarBHillJSMorganDJNationRLStylliSSet al

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This Questions and Answers document introduces the concept of a double negative nonclinical scenario (negative hERG assay and negative in vivo QTc Study) to demonstrate that a drug does not produce a clinically relevant QT liability

Cell 40, 301309
